STAT 527B/447B

• Course Outline

• Jan. 9

• Jan. 11

• Jan. 16

• Lecture Scribblings: Jan. 16

• Jan. 18 Lecture Notes

• Analysis of Variance/Covariance in Multiple Regression (revised Jan. 29)

• Jan. 23 Lecture Notes

• Jan. 25 Lecture Notes

• Jan. 30 Lecture Notes

• Feb. 1 Lecture Notes

• Feb. 6 Lecture Notes

• Feb. 8: Model Building Examples

• Feb. 8 Lecture Notes

• Feb. 13: Logistic Regression Examples

• Feb. 13 Lecture Notes

• Feb. 15 Lecture Notes

• Feb. 27 Lecture Notes

• Feb. 27: Logistic Regression Examples (2)

• Lecture Notes, Mar. 1

• Mar. 6: Logistic Regression Examples (3)

• Mar. 6, Lecture Notes

• Mar. 13, Lecture Notes

• Mar. 15 Lecture Notes

• More on 2x2 Tables

• Mar. 20 Lecture Notes

• Mar. 22 Lecture Notes

• Mar. 27 Lecture Notes

• Mar. 29 Lecture Notes

• April 3 Lecture Notes

• April 5 Lecture Notes

• April 10 Lecture Notes

• April 12 Lecture Notes

Assigned Reading

• Simple Correlation and Regression (Review Material)

• An Introduction to Epidemiology

  • a very brief introduction to the basics

• Multiple Linear and Regression

  • note - the notation in this material doesn't quite match the lectures

Logistic Regression and Analysis of Risks

• Chapter 7 in the on-line text by Annette Dobson

• more formal notes on Logistic Regression

• Quick review of maximum likelihood

• Sections 2(Quantifying disease in populations) & 3 (Comparing Disease Rates) in Epidemiology for the Uninitiated

• Survival Analysis

• Additional Topics, Parts 1 & 2
  
  

Assignments, Exercises

• Assignment 1 (***Now due in class Feb. 6***)

• Data for Assignment 1, Question 2 (in .csv format)

  • Download the file and use read.csv()

• Data for Assignment 1, Question 2 (in R format)

  • Download the fille by right clicking and using “Save as ...”

  • Use load() to bring the data into R

• Assignment 1: additional question for graduate students

• Assignment 1: Model Solutions

• Assignment 2

• Answers to e-mail queries regarding Assignment 2

• More answers to e-mail queries regarding Assignment 2

• Assignment 2 Question for Graduate Students

• Data for Assignment 2 Graduate Student question

• Data for Assignment 2 - hormone.rda

• Data for Assignment 2 - hormone.csv

• Data for Assignment 2 - lethal1.rda

• Data for Assignment 2 - lethal1.csv

• Data for Assignment 2 - lethal2.rda

• Data for Assignment 2 - lethal2.csv

• Sample Midterm

• Assignment 2 Model Solutions

• Assignment 3 - due Mar. 22

• Data for Assignment 3, Question 2

• Assignment for Grad students, due Thursday, April 5 
• First paper for grad student assignment
• Second paper for grad student assignment

Assignment 3 Solutions

• Assignment 4, due Tuesday, April 3

  • Data for assignment 4

Assignment 4 Solutions

• Assignment 5, due Thursday, April 12
• Data for assignment 5

Assignment 5 Solutions

Sample Final Exam

Sample Final Exam Solutions [note modification to question 2b]

Stuff to do with computing in R

• R examples for Logistic Regression

• icu.raw file

• transf.raw file

• Example of R code for Survival Analysis

  • Example Data file

• atRiskFunctions.rda: functions need to label survival plot with at risk numbers

• R code for Poisson model examples
  

  • ZIP file with data for Poisson model examples

Supplementary Materials

• Epidemiology for the Uninitiated

  • This is a more extensive set of web-pages. I will suggest readings as we proceed.

• Epidemiology: Introduction to Epidemiologic Methods

  • Twenty video-taped lectures from the University of Washington Dept. of Epidemiology

  • For the very ambitious!

Design, Analysis and Reporting Randomized Clinical Trials

The Consort Group is a collective of clinicians, epidemiologists and statisticians whose aim is to improve the conduct and reporting of randomized clinical trials. They have developed a set of suggested guidelines known as the Consort Statement. A subsequent document provides more detail, especially with regard to the statistical analysis of clinical trials.

Problems with Stepwise Regression

STATA is a commercial statistics package which has very good WWW-based support material, included a FAQ (frequently asked questions) list which includes this page with comments from Frank Harrell and Ronan Conroy